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Figure 3 | Molecular Pain

Figure 3

From: Protein kinase Cδ mediates histamine-evoked itch and responses in pruriceptors

Figure 3

Localization of PKCδ and markers of peptidergic and non-peptidergic dorsal root ganglion neurons. A. Representative images of CGRP+, PKCδ+, and co-expressing (Merge) DRG neurons. B. Graphical representation of total neurons counted and degree of overlap (n = number of neurons). C, D. Representative images of IB4+, PKCδ+, and IB4+/PKCδ + neurons and illustration of overlap. E, F. Representative images of TRPV1+, PKCδ+, and TRPV+/PKCδ + neurons and illustration of overlap. Inset demonstrates TRPV1 antibody stain in TRPV1-KO mice. (Scale bar = 50 μm; Arrowheads indicate example cells that express both markers).

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