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Figure 5 | Molecular Pain

Figure 5

From: Inflammatory and neuropathic pain animals exhibit distinct responses to innocuous thermal and motoric challenges

Figure 5

Mobility on ThermalTrack as a function of increasing levels of challenge. Number of switches from one compartment to the other (within 300 seconds time windows), as a function of floor temperature in the dark compartment (indicated in each panel, ranging from 25–42°C), while light compartment floor temperature is kept at 25°C, over 30 minutes of monitoring (t1 – t6 are 5-minute consecutive windows), and as a function of type of injury (blue circles = control, red squares = SNI, green diamonds = Carrageenan rats). In each panel, statistical outcome of planned comparison between SNI and Carrageenan (Carr) groups are indicated. There is no difference between SNI and Carr groups at intermediate levels of challenge. However, the two groups of animals behave differently at low and high levels of challenge. Bars are 95% confidence intervals. Note the increase in variability of behavior with increase in challenge level.

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