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Figure 6 | Molecular Pain

Figure 6

From: Inflammatory and neuropathic pain animals exhibit distinct responses to innocuous thermal and motoric challenges

Figure 6

Behavior on Angle as a function of increasing levels of challenge. Amount of time spent in the dark compartment in seconds (maximum = 300 seconds), as a function of inclination of the dark compartment (indicated in each panel ranging from 0–55°), while light compartment floor is kept at 0°, over 30 minutes of monitoring (t1 – t6 are 5-minute consecutive windows), and as a function of type of injury (blue circles = control, red squares = SNI, green diamonds = Carrageenan rats). In each panel, statistical outcome of planned comparison between SNI and Carrageenan (Carr) groups are indicated. The largest difference between SNI and Carr groups is at 25° inclination. At 55° inclination, there is a strong interaction between time and groups, where we observe no difference between groups for early time windows, and a large difference between control and injured animals. Bars are 95% confidence intervals. Note that variability increases for intermediate challenge levels in the later time bins.

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