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Figure 7 | Molecular Pain

Figure 7

From: Comparison of P2X and TRPV1 receptors in ganglia or primary culture of trigeminal neurons and their modulation by NGF or serotonin

Figure 7

Functional characterization of rat and mouse TG neurons. A, fraction of cells responding to α, β-meATP (independently from their response to capsaicin), to capsaicin (independently from their response to α, β-meATP) or to both agonists for rat (left panel; n = 33) and mouse (right panel; n = 50). B, persistence of the responsiveness of rat TG neurons in culture to α, β-meATP and capsaicin. a, Proportion of cells responding to α, β-meATP (black bars; n = 7, 7, 10 cell cultures for the 1st, 2nd and 3rd day, respectively) and capsaicin (grey bars; n = 7, 8 and 8 cell cultures for the 1st, 2nd and 3rd day). b, peak amplitude of currents elicited by α, β-meATP (black bars; n = 22, 11 and 31 cells for the 1st, 2nd and 3rd day, respectively) and capsaicin (grey bars; n = 16, 13 and 10 cells for the 1st, 2nd and 3rd day). Only cells responding to the agonist were included in the current analysis.

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