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Table 1 P2X or TRPV1 of small, medium and large TG neurons in ganglia or in culture

From: Comparison of P2X and TRPV1 receptors in ganglia or primary culture of trigeminal neurons and their modulation by NGF or serotonin

P2X 3
  Rat Mouse
  Small Medium Large Small Medium Large
Tissue 44 ± 4% 33 ± 3% 23 ± 4% 49 ± 3% 36 ± 4% 15 ± 4%
24 h 55 ± 3% 28 ± 3% 17 ± 2% 60 ± 4% 31 ± 3% 9 ± 2%
48 h 54 ± 2% 33 ± 3% 13 ± 3% 56 ± 4% 29 ± 3% 15 ± 2%
72 h 58 ± 5% 30 ± 4% 12 ± 2% 62 ± 5% 30 ± 4% 8 ± 2%
96 h 56 ± 4% 31 ± 4% 13 ± 3% 60 ± 4% 33 ± 3% 7 ± 2%
P2X 2
  Rat Mouse
  Small Medium Large Small Medium Large
Tissue 30 ± 2% 55 ± 3% 15 ± 4% 32 ± 3% 52 ± 2% 16 ± 4%
24 h 34 ± 4% 56 ± 3% 10 ± 4% 36 ± 2% 51 ± 3% 13 ± 3%
48 h 36 ± 4% 57 ± 4% 7 ± 3% 29 ± 3% 55 ± 3% 16 ± 4%
72 h 33 ± 3% 57 ± 4% 10 ± 3% 22 ± 3% 65 ± 2% 13 ± 3%
96 h 34 ± 3% 60 ± 2% 6 ± 3% 21 ± 3% 69 ± 6% 10 ± 3%
TRPV1
  Rat Mouse
  Small Medium Large Small Medium Large
Tissue 60 ± 3% 31 ± 4% 9 ± 3% 59 ± 2% 32 ± 3% 9 ± 2%
24 h 65 ± 4% 29 ± 4% 6 ± 2% 66 ± 2% 31 ± 3% 3 ± 1%
48 h 64 ± 2% 29 ± 3% 7 ± 2% 70 ± 3% 28 ± 3% 2 ± 1%
72 h 66 ± 4% 29 ± 2% 5 ± 2% 68 ± 5% 30 ± 4% 2 ± 1%
96 h 68 ± 4% 27 ± 2% 5 ± 2% 72 ± 4% 26 ± 3% 2 ± 1%
  1. Data are % distribution of P2X3, P2X2 or TRPV1 immunopositive neurons according to their somatic size (small: dia <15 μm; medium: 15 μm–25 μm; large: dia > 25 μm). In each box 100% = the total number of cells immunoreactive for the given receptor.
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Molecular Pain

ISSN: 1744-8069

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