Figure 5

Voltage-dependent K⁺ currents in hypoxia. Current recordings (holding potential -80 mV, ΔV 10 mV) in control, hypoxia and washout revealing different reactions of K⁺ currents to hypoxia. A) Most neurones (63%) showed a decreased K⁺ current during hypoxia which was irreversible in some cells (n = 17). B) Another group of neurones (26%, n = 7) displayed a reversible increase in K⁺ current. C) Some neurones showed no (11%) or only small differences in K⁺ currents during hypoxia (n = 3). Current-voltage relations shown right. Bath: sodium-free choline chloride, pipette: potassium fluoride.