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Table 1 Application of hypoxia and subsequently of toxin.

From: Moderate hypoxia influences excitability and blocks dendrotoxin sensitive K+ currents in rat primary sensory neurones

 

Control

Hypoxia

Washout

Toxin

Hypoxia+ Toxin

Washout

α-DTX (n = 7)

2.92 ± 0.73

2.36 ± 0.69 †

2.53 ± 0.66 (n.s.)

1.64 ± 0.51 †

1.60 ± 0.48 (n.s.)

n.d.

TEA (n = 8)

4.12 ± 0.62

3.65 ± 0.52 †

3.34 ± 0.48 (n.s.)

2.02 ± 0.35 †

1.79 ± 0.32 *

n.d.

DTX-K (n = 6)

3.14 ± 0.32

2.46 ± 0.28 †

n.d.

n.d.

2.08 ± 0.31 *

1.56 ± 0.63 (n = 2, n.d.)

TsTX-K (n = 5)

2.91 ± 0.38

2.53 ± 0.43 *

n.d.

n.d.

1.92 ± 0.34 †

1.77 ± 0.20 (n.s.)

MgTX (n = 7)

2.41 ± 0.48

1.89 ± 0.37 *

n.d.

n.d.

1.55 ± 0.30 (n.s.)

1.82 ± 0.59 (n.s.)

AgTX-2 (n = 2)

2.48

2.15

n.d.

n.d.

1.61 ± 0.17

1.25 ±

  1. K+ current amplitude of different neurones in nA ± S.E.M. * p < 0.05, † p < 0.01 when tested against the preceding value, n.s. = not significant, n.d. not determined