Skip to main content
Figure 4 | Molecular Pain

Figure 4

From: Impaired inflammatory pain and thermal hyperalgesia in mice expressing neuron-specific dominant negative mitogen activated protein kinase kinase (MEK)

Figure 4

Basal phosphorylation of ERK is similar in the wild type and DN MEK mice spinal cords. A, Representative immunoblot of mouse spinal cord homogenates using a phospho-ERK1/2 antibody (top) or a total ERK1/2 antibody (bottom). The arrows show the position of the 44 kDa ERK 1 and 42 kDa ERK 2 isoforms. Quantification of ERK activation in male (B) and female (C) mice. Phospho-ERK bands were densitized and normalized to total ERK from the same samples. n = 8–9 (male mice), and 8–9 (female mice).

Back to article page