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Figure 6 | Molecular Pain

Figure 6

From: Impaired inflammatory pain and thermal hyperalgesia in mice expressing neuron-specific dominant negative mitogen activated protein kinase kinase (MEK)

Figure 6

Representative electron micrographs of cross sections of the sciatic nerves of A) wild type and B) DN MEK mice. Small diameter unmyelinated fibers (UM) are often present as encapsulated bunches of fibers in between the myelinated fibers. Thick arrowheads point to the Schwann cells of the large diameter myelinated fibers (LM). Small arrows point to the Schwann cells of the small diameter myelinated fibers (SM). S represents the Schwann cell of the unmyelinated fibers. C) Bar graph showing the mean number of unmyelinated fibers per 100 μm2. ***P < 0.001, n = 363 and 377 images from 2 wild type and 2 DN MEK mice sciatic nerves respectively.

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Molecular Pain

ISSN: 1744-8069

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