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Figure 4 | Molecular Pain

Figure 4

From: Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-κB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine

Figure 4

mGlu2/3 expression in DRG neuronal cultures following the inhibition of the NF-κB transcriptional activity. (A-B) Immunocytochemical analysis of mGlu2/3 in mouse DRG cultures treated with vehicle or CAPE (2.5 μg/ml for 30 min) respectively. (C) Upper Panel: In-Cell western image for mGluR2/3 (green fluorescence) and MAP-2 (red fluorescence) in mouse DRG cultures in the absence or presence of CAPE (2.5 μg/ml for 30 min). Lower panel: Quantification of mGlu2/3 expression normalized to MAP-2 protein expression. Infrared fluorescence levels were measured 4 days after CAPE incubation. Results are expressed as the mean ± SEM of 6 different determinations. *p < 0.05, vs vehicle (Student's t test).

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Molecular Pain

ISSN: 1744-8069

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