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Figure 4 | Molecular Pain

Figure 4

From: Forebrain overexpression of CaMKII abolishes cingulate long term depression and reduces mechanical allodynia and thermal hyperalgesia

Figure 4

Behavioral nociceptive responses to noxious heat, mechanical pressure and formalin injection were not altered in αCaMKII-F89G transgenic mice. A-B. Behavioral nociceptive responses to noxious heating in the tail-flick test at two different heating intensities (A) and the hot-plate test at three different temperatures (50, 52, 55°C) (B). No significant differences were found between wild-type and αCaMKII-F89G transgenic mice in any test. C-D. No significant differences were found in hind paw withdrawal responses to noxious heating or mechanical pressure. E. Behavioral nociceptive responses to hindpaw formalin injection, plotted in 5-min intervals, in wild type mice as compared to αCaMKII-F89G transgenic mice. No significant difference was found between wild-type and transgenic mice.

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Molecular Pain

ISSN: 1744-8069

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