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Figure 8 | Molecular Pain

Figure 8

From: The μ opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway

Figure 8

Cultured Dorsal Root Ganglion Neurones co-express TRPV1 and MOP. (A) DAPI stain (blue) shows cell nuclei of neurones as well as accessory cells. (B) Labelling with anti-MOP antibody, visualised with a FITC-conjugated secondary antibody, shows expression of MOP protein in cells with neuronal morphology, but not accessory cells. (C) TRPV1 protein (red) was visualised using a TRPV1 antibody with Cy3-conjugated secondary antibody. (D) Overlay of panels A, B and C shows co-expression of TRPV1 and MOP (yellow) in cultured DRG neurones. Scale bar = 12 μm.

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