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Figure 8 | Molecular Pain

Figure 8

From: The effects of protein phosphatase inhibitors on the duration of central sensitization of rat dorsal horn neurons following injection of capsaicin

Figure 8

Rate histograms show the responses of a dorsal horn neuron to mechanical stimuli, the changes produced by intradermal injection of capsaicin and the effects of Fostriecin perfusion through the microdialysis fiber 1 h after i.d. injection of capsaicin. Top row: baseline background activity and responses to brush, press, and pinch. Second row: 30 min after capsaicin injection. Third row: 1 h after capsaicin injection. Fostriecin perfusion through the microdialysis fiber started. Fourth row: 2 h after capsaicin injection (Fostriecin perfusion stopped at 1.5 h after capsaicin injection). Bottom row: 3 h after capsaicin injection. Horizontal lines above responses in the top row indicate when the stimuli were applied.

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