Effect of post-treatment with the phosphatase inhibitor fostriecin (3 μM; n = 12) or ACSF (n = 10) on increased activity of nociceptive dorsal horn neurons induced by capsaicin injection (arrows). 1 h after capsaicin injection, fostriecin or ACSF was continuously infused for 30 minutes (upper horizontal bars). The value before capsaicin injection was recorded as baseline. (A) Background activity; (B) Response to brush stimulus; (C) Response to press; (D) Response to pinch. ●○, P < 0.05, significant difference from baseline in each different line. All values are presented as mean ± SEM.