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Figure 6 | Molecular Pain

Figure 6

From: Genetic reduction of chronic muscle pain in mice lacking calcium/calmodulin-stimulated adenylyl cyclases

Figure 6

Rescue of mechanical allodynia by bilateral injection of forskolin into the ACC. A. Site of bilateral injection of forskolin into the ACC in coronal plane. Injections were made at 0.7 mm anterior to the bregma, 0.3 mm lateral to the midline and 1.75 mm ventral to the skull. B. Bilateral ACC microinjection sites of vehicle (in green) and forskolin (in red). The coronal section is 0.7 mm anterior to the bregma. C. Forskolin rescued behavioral allodynia in carrageenan induced chronic muscle pain in AC1&8 DKO mice on day 9 on the ipsilateral side. Forskolin injection, n = 6 mice; Vehicle injection, n = 5 mice. p < 0.05. *Significant difference from vehicle injection.

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