Figure 2

Shortening of the onset time of ischemia-induced inward currents by capsaicin stimulation. A). A sample trace shows ischemia-induced inward current in a lamina V neuron of a rat at the age of 9 days old. B). A sample trace shows ischemia-induced inward currents in a lamina V neuron of another rat at the age of 9 days old. In this experiment, focal stimulation (100 μA, 100 Hz) was applied to dorsal root entry zone while ischemic bath solution was applied to the spinal cord slice preparation. Note that in this sample trace, stimulation artifacts were superimposed on the inward currents. C). Pooled results from experiments represented in A (open bar, n = 6) and B (solid bar, n = 4). All animals used were at the age of 9 days old.