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Figure 1 | Molecular Pain

Figure 1

From: Frequency-dependent ERK phosphorylation in spinal neurons by electric stimulation of the sciatic nerve and the role in electrophysiological activity

Figure 1

Expression of pERK in the ipsilateral L4/5 dorsal horn after electrical stimuli was frequency-dependent. A-D: Photomicrographs show pERK expression in spinal cord of rats that received sham operations without electrical stimulation (A), or 16 pulses of 3 mA electrical stimulation at frequencies of 0.05 Hz (B), 0.5 Hz (C), and 10 Hz (D) to the sciatic nerve. E-G: Double-immunofluorescence for pERK (green, E) and NeuN (red, F) after electrical stimulation at 3 mA/0.5 Hz to the sciatic nerve. Double staining appears yellow (G). Scale bars, 100 μm.

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