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Table 5 Association of six GABRB1 markers with movement scores in sciatica patients

From: Do motor control genes contribute to interindividual variability in decreased movement in patients with pain?

dbSNP ID

Allele1

Allele2

Genotype

Count

Movement Score

p Value*

rs4694846

A

G

1/1

125

11.35

0.1862

   

1/2

136

10.85

 
   

2/2

49

10.81

 

rs17461905

A

G

1/1

222

10.83

0.1219

   

1/2

84

11.46

 
   

2/2

4

11.73

 

rs13107066

A

C

1/1

103

11.17

0.8874

   

1/2

136

10.84

 
   

2/2

71

11.09

 

rs6813436

A

G

1/1

4

10.53

0.6383

   

1/2

68

11.29

 
   

2/2

238

10.96

 

rs7439087

A

G

1/1

148

10.73

0.2294

   

1/2

131

11.29

 
   

2/2

31

11.19

 

rs 6290

T

C

1/2

42

10.93

0.8447

   

2/2

268

11.04

 

Haplotype analysis

No. of haplotype 211212 (GAAGAC)

  
   

2

8

8.5

0.0025

   

1

52

10.3

 
   

0

248

11.3

 
  1. p values shown are for additive model, which assumes that each copy of the uncommon allele alters the movement score by a similar amount, and uncorrected for examining 121 SNPs in 22 haplotype blocks in 14 genes.
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Molecular Pain

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