Figure 2
From: Morphine reduces local cytokine expression and neutrophil infiltration after incision
Hind paw skin cytokine levels at baseline and 2 hours after incision. For these experiments skin was harvested at baseline and 2 hours after incision near the end of the measured morphine analgesic effects. Mice were given saline or morphine of various doses immediately prior to the incisions being made. These analyses used tissue from 6 mice per treatment condition. The statistical significance of incised skin versus incised with prior morphine treatment was assessed. **p < 0.01.