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Figure 2 | Molecular Pain

Figure 2

From: Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice

Figure 2

Effect of intraperitoneal (i.p.) injection of L-NAME or D-NAME on mechanical pain hypersensitivity on day 7 after L5 spinal nerve injury in WT mice. Paw withdrawal responses to 0.24 mN (A and C) and 4.33 mN (B and D) mechanical stimuli on the ipsilateral (A and B) and contralateral (C and D) sides. *P < 0.05, **P < 0.01 vs the corresponding baseline. ##P < 0.01 vs the post-drug, D-NAME-treated group.

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