Figure 4
From: Comparison of evoked vs. spontaneous tics in a patient with trigeminal neuralgia (tic doloureux)
Activation (increased top panel and decreased lower panel) in brain regions by spontaneous tics. Activation maps based on GLM-based analysis using the spontaneous EV (n = 13 tics). Increases were observed in a number of areas (See Table 3) and examples of these are shown here. Activation was present in the lateral frontal gyrus (LFG), the anterior cingulate (ACC), Insula (Ins), posterior thalamus (Thal), pontine nuclei (PN), ventral tegmental area (VTA), cerebellum (Cb) and inferior parietal lobe (IPL). Spontaneous tics significantly decreased baseline levels of brain activity in several areas. These include the anterior hypothalamus (Hyp), posterior cingulate cortex (PCC), and middle parietal lobe (MPL). R = Right and L = Left.