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Figure 5 | Molecular Pain

Figure 5

From: Requirement of extracellular signal-regulated kinase/mitogen-activated protein kinase for long-term potentiation in adult mouse anterior cingulate cortex

Figure 5

MEK inhibitors do not affect the AMPA receptor-mediated EPSCs. A, B: Bath application of PD98059 (50 μM, n = 10) or U0126 (50 μM, n = 6) does not affect the AMPA-receptor-mediated EPSCs. The insets show averages of six EPSCs before (Control; open) and after (PD98059 or U0126; solid) application of PD98059 or U0126. The dashed line indicates the mean basal synaptic response. Decay time versus rise time for AMPA receptor-mediated EPSCs before (Control; open) and after (PD98059 or U0126; solid) application of PD98059 or U0126.

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