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Figure 3 | Molecular Pain

Figure 3

From: Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists

Figure 3

Trichloro(sulfanyl)ethyl benzamides inhibit AITC (80 μM) induced increase in intracellular calcium and inward currents in CHO cells stably expressing human TRPA1 (A-D). Effect of AMG9090 (A), AMG5445 (B), AMG2504 (C), and AMG7160 (D) on AITC-induced increase in intracellular calcium in CHO cells expressing human TRPA1 measured in an aequorin-readout assay. Open circles represent the response of cells to the compound itself in the absence of agonist. Each point in the graph is an average ± SEM of an experiment conducted in triplicate.

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Molecular Pain

ISSN: 1744-8069

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