Figure 2From: A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition AP18 specifically blocks TRPA1. Calcium influx (FLIPR) in HEK cells transiently transfected with the indicated cDNAs in response to 200 nM capsaicin (TRPV1), 150 μM 2-APB (TRPV2), 30 μM 2-APB (TRPV3), 20 μM 4alpha-PDD (TRPV4), 20 μM menthol (TRPM8), and 80 μM cinnamaldehyde (TRPA1). Values are given as a percentage of agonist response in the absence of AP18.Back to article page