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Figure 3 | Molecular Pain

Figure 3

From: Activation of the neurokinin-1 receptor by substance P triggers the release of substance P from cultured adult rat dorsal root ganglion neurons

Figure 3

Time-course studies of the SP-induced neurokinin-1 receptor expression in the cytosolic and membrane fractions from cultured adult rat DRG neurons. (A) Representative blots of the neurokinin-1 receptor expression in the cytosolic and membrane fractions from cultured DRG neurons exposed to SP for 10 to 360 min. All data have been quantified by normalizing the neurokinin-1 receptor expression level of control in the membrane (B) or cytosolic (C) fraction at 10 min, respectively. The data are expressed as the means ± S.E.M. (bars) from 3 separate experiments. # denotes a p < 0.05 as compared to the effect of untreated control at 10 min, *p < 0.05 and **p < 0.01 versus the effect of the untreated control at the same time by a one-way analysis of variance followed by Bonferroni's test.

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