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Figure 2 | Molecular Pain

Figure 2

From: Techniques for assessing knee joint pain in arthritis

Figure 2

Time course of the changes of three outcome measures in rats with a kaolin/carrageenan (K/C)-induced arthritis. (A) Circumference of the knee before and after K/C injection. (B) Angle at which the knee could be extended before eliciting struggling behavior in the rat. (C) Vocalization threshold of the compression force, which was applied to the knee. Post-injection time is expressed as hours (h) or days (d) after K/C injection. Pre-injection control was taken one day before the injection (-1 d). Asterisks indicate values significantly different from the pre-injection control value by one-way ANOVA followed by the Dunnett's posthoc test (n = 10). Symbols and error bars represent mean ± SE. Reprinted from [33], Copyright 2002, with permission from Elsevier.

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