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Table 1 Quantitative analysis of microglia density and percentage of particular microglia type in pain-related brain structures (Ipsi. and Contral. indicate surgery and intact sides, respectively).

From: Selective activation of microglia in spinal cord but not higher cortical regions following nerve injury in adult mouse

     Cell type (%)
Region   Density (number/mm 2 ) Ramified Hypertrophied Mono-polar Bipolar
   Ipsi. Contral. Ipsi. Contral. Ipsi. Contral. Ipsi. Contral. Ipsi. Contral.
ACC control 191.0 ± 27.6 200.0 ± 38.4 95.7 ± 0.3 94.4 ± 0.5 0 0 4.3 ± 0.3 4.4 ± 0.3 0 1.2 ± 0.4
  injury 181.7 ± 13.6 188.7 ± 13.5 92.1 ± 0.4 92.3 ± 1.7 0 0 5.7 ± 0.3 4.4 ± 0.2 2.2 ± 0.7 3.3 ± 1.7
Prefrontal control 193.3 ± 27.6 199.7 ± 28.9 94.6 ± 0.9 95.6 ± 0.9 0 0 4.1 ± 0.4 4.3 ± 0.9 1.3 ± 0.2 0
Cortex injury 184.7 ± 14.5 180.3 ± 18.9 89.9 ± 2.5 90.1 ± 2.2 2.6 ± 1.5 0 6.3 ± 0.3 7.3 ± 1.3 1.2 ± 0.7 2.6 ± 1.4
Somatosensory control 169.3 ± 17.6 152.0 ± 17.6 97.2 ± 0.9 98.8 ± 0.5 0 0 2.1 ± 0.5 1.2 ± 0.5 0.7 ± 0.4 0
Cortex injury 184.0 ± 24.5 178.3 ± 13.6 92.8 ± 2.4 94.9 ± 0.6 0 0 4.5 ± 2.1 5.1 ± 0.6 2.7 ± 0.6 0
Insular cortex control 189.0 ± 11.8 209.2 ± 16.8 94.5 ± 0.6 96.6 ± 0.6 0 0 4.8 ± 0.3 2.9 ± 0.3 0.7 ± 0.3 0.5 ± 0.5
  injury 176.7 ± 22.6 174.3 ± 18.2 98.0 ± 0.3 96.3 ± 0.6 0 0 1.5 ± 0.3 2.7 ± 0.3 0.5 ± 0.3 1.0 ± 0.6
Amygdala control 194.0 ± 21.7 176.7 ± 26.3 94.2 ± 1.2 98.0 ± 1.3 1.1 ± 0.6 0 2.6 ± 0.2 2.0 ± 1.3 2.1 ± 0.6 0
  injury 184.3 ± 12.5 183.3 ± 14.2 93.9 ± 1.8 96.3 ± 2.0 0 0 3.3 ± 0.9 3.7 ± 2.0 2.7 ± 0.9 0
Hippocampus control 182.3 ± 20.8 183.3 ± 13.6 93.3 ± 0.7 92.5 ± 0.9 0 0 4.3 ± 0.7 4.3 ± 0.5 2.4 ± 0.4 3.2 ± 0.5
  injury 176.3 ± 12.7 185.0 ± 15.0 91.1 ± 2.3 88.7 ± 2.2 0 1.5 ± 0.6 7.0 ± 1.2 6.7 ± 0.6 1.9 ± 1.2 3.1 ± 3.0
Thalamus control 145.4 ± 34.1 124.2 ± 37.1 96.6 ± 0.6 94.0 ± 0.9 0 0 3.4 ± 0.6 4.5 ± 0.9 0 1.5 ± 0.2
  injury 131.3 ± 46.5 139.4 ± 37.9 86.7 ± 2.3 89.8 ± 2.1 0 0 6.6 ± 1.2 7.3 ± 1.2 6.7 ± 1.2 2.9 ± 0.9
PAG control 105.7 ± 12.3 104.0 ± 20.4 92.7 ± 2.6 90.4 ± 3.1 0 0 4.0 ± 1.6 7.6 ± 1.6 3.3 ± 1.1 1.9 ± 0.8
  injury 130.0 ± 25.0 125.3 ± 15.5 88.4 ± 1.8 86.1 ± 2.3 0 0 7.3 ± 1.2 7.5 ± 1.4 4.3 ± 0.8 6.4 ± 1.0
RVM control 79.3 ± 12.5 77.7 ± 17.0 91.8 ± 0.9 90.5 ± 1.2 0 0 5.1 ± 0.3 4.3 ± 0.3 3.1 ± 0.6 5.2 ± 0.9
  injury 78.7 ± 14.6 82.3 ± 12.3 89.5 ± 2.6 91.3 ± 0.7 0 0 6.4 ± 1.4 4.0 ± 0.9 4.1 ± 1.2 4.7 ± 0.7