Results of quantitative analyses of Na
1.7 expression within nerve fibers in normal and painful samples. A-F. The nerve area and pixel intensity of Nav1.7 expression within N52/PGP9.5-identified nerve fibers was quantified within different regions in normal and painful samples. A and B. The nerve area (A) and pixel intensity (B) of Nav1.7 expression was not significantly different within the pulp horns of normal and painful samples. C-F. The nerve area of Nav1.7 expression was significantly greater within coronal (C) and upper radicular (E) axon bundles in painful samples, but with no difference between normal and painful samples in pixel intensity within these same regions (D, F). ** = p < 0.01, *** = p < 0.001.