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Table 1 Characteristics of synaptic events mediated by GABAA and AMPA receptors.

From: Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition

 

Amplitude (pA)

τR (ms)

τD (ms)

Frequency (Hz)

n

GABAA-R mIPSCs

11.7 ± 0.8

3.17 ± 0.55

29.06 ± 3.83

0.13 ± 0.03

6

GABAA-R sIPSCs

11.1 ± 1.5

3.97 ± 0.72

30.35 ± 0.86

0.12 ± 0.02

6

AMPA-R mEPSCs

-14.1 ± 0.9

1.27 ± 0.07

3.91 ± 0.17

0.81 ± 0.17

14

AMPA-R sEPSCs

-16.3 ± 0.8

1.31 ± 0.10

4.23 ± 0.26

1.26 ± 0.47

16

  1. Mean values and SEM are shown for amplitude, rise and decaying monoexponential time constants (τR and τD, respectively) and frequency of occurrence of spontaneous (sIPSCs and sEPSCs) and miniature (mIPSCs and mEPSCs) events. Note that the mean values were not statistically different while recorded in the absence (spontaneous) or in the presence of tetrodotoxin (miniatures).
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Molecular Pain

ISSN: 1744-8069

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