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Table 1 The P610T SCN9A mutation detected in this study is in bold, and for comparison the corresponding amino acids from various species are included. Note that PPM residues 609–611 are highly but not totally conserved among mammalian species.

From: Compound heterozygosity in sodium channel Nav1.7 in a family with hereditary erythermalgia

Homo sapiens

NISQASRSPPMLPVNGKMHSA

Macaca mulatta

NISQASRSPP ILPVNGKMHSA

Equus caballus

NISQASRSPP MLPVNGKMHSA

Bos taurus

NISQASRSPP VLPVNGKMHSA

Canis familiaris

NISQASRSPP VLPVNGKMHSA

Rattus norvegicus

NISQASRSPP VLPVNGKMHSA

Mus musculus

NISQASRSPP VLPVNGKMHSA

Cavia porcellus

NISQASRSPP MLPVNGKMHSA

Dasypus novemcinctus

NISQASRSPP MLPVNGKMHSA

Monodelphis domestica

NISQASRSPRMLPVNGKMHSA

Ornithorhyncus anatinus

NLSQASRSLRMLPVNGKMHST

Gallus gallus

NISQASRPLTLFPVNGKMHST