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Figure 3 | Molecular Pain

Figure 3

From: Involvement of P311 in the affective, but not in the sensory component of pain

Figure 3

Defect of pain affection in P311-/- mice. Time spent in each compartment was monitored during the pre-test (day 1) and post-test day (day 5) of the experiments. A. In wild-type mice, formalin (n = 16) but not saline (n = 12) induced conditioned place avoidance. Conditioned place avoidance was induced by formalin in wild-type mice (n = 16), but not in P311-/- mice (n = 16). Student's t-test, *P < 0.05, ***P < 0.001. B. LiCl (150 mg/kg, i.p.) induced conditioned place aversion in both wild-type (n = 10) and P311-/- mice (n = 10) in a comparable manner. Student's t-test, ***P < 0.001.

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