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Figure 11 | Molecular Pain

Figure 11

From: PKA and ERK, but not PKC, in the amygdala contribute to pain-related synaptic plasticity and behavior

Figure 11

Histologic verification of drug application sites. Standard diagrams [adapted from [54]] show coronal sections through the right brain hemisphere at different levels posterior to bregma (-1.88 mm and -2.12 mm). Symbols show the positions of the tips of the microdialysis probe (length of exposed membrane = 1 mm) in the CeLC (A-C) and striatum (D, placement control) in the behavioral experiments. (A) Application sites of KT5720, n = 11. (B) U0126, n = 12, filled circles; U0124, n = 3, open circles. (C) GF109203X, n = 9. (D) KT5720, n = 4, filled circles; U0126, n = 4, open circles. CeM, CeL, CeLC: medial, lateral and laterocapsular divisions of the central nucleus of the amygdala. Calibration bar (1 mm) applies to each diagram in A-D.

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