Figure 5

RTX does not affect normal mechanical sensitivity or rotarod performance. Withdrawal force latencies were similar for vehicle and RTX treated animals except after inflammation, where there was a significant difference (*P < 0.05, Mann-Whitney rank sum test) between the two groups (A). Data presented as a median normalized threshold (bars: interquartile range). Pre-inflammation values for both vehicle and RTX-treated groups were all significant versus the post-inflammation value (Krukal-Wallis ANOVA, P < 0.05). Values are represented by a median normalized threshold and the interquartile range is denoted by the bars. Rotarod performance was identical for both groups (B).