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Figure 2 | Molecular Pain

Figure 2

From: Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves

Figure 2

2D-DIGE DeCyder BVA (Biological Variation Analysis) showing a representative gel image with labelled sample of control and neuroma. Changes in protein expression were compared between 4 time-points (3 day, 1 week, 2 week and 3 week neuromas) and controls after normalisation with a pooled internal standard. The master gel image shows the locations of differentially expressed proteins (≥1.75 change in abundance; p < 0.05; n = 3). The lower part of the figure shows an enlarged region of the gel and 3-D view of up-regulated spot 1666 as an example (lower left). Spot no 1666 (protein DJ-1) is shown in detail as displaying increased expression during neuroma formation (lower right).

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Molecular Pain

ISSN: 1744-8069

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