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Figure 1 | Molecular Pain

Figure 1

From: The chemokine CXCL1/growth related oncogene increases sodium currents and neuronal excitability in small diameter sensory neurons

Figure 1

GRO/KC incubated cells have Na+ currents that are qualitatively similar to those seen in control cells. A. Examples of current traces elicited from holding potential of -80 mV (darker, smaller traces) or -50 mV. As in control cells, the currents elicited from -80 mV have a faster component, which is TTX-sensitive (see text). B. Persistent Na+ currents activating at -60 to -50 mV were not observed. Average leak-subtracted steady state current is plotted against the step potential. Holding potential was -80 mV.

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