Figure 4

Lower doses of GRO/KC do not increase Na⁺ current density. Current densities were measured as in Figure 1, after overnight exposure to the indicated concentration of GRO/KC. For each concentration tested, data have been normalized to the control values obtained in cells from the same cultures with no GRO/KC treatment. *, significantly different from control. TTX-R current at 0 mV was used for this analysis. N = 27 cells for 0.06 nM dose (plus 17 control cells from the same cultures); 10 cells for 0.28 nM dose (plus 14 control cells), and 54 cells for 1.5 nM dose (plus 53 control cells).