Cell and AP Properties | IB4-negative cells | IB4-positive cells | ||
---|---|---|---|---|
 | Control | GRO/KC | Control | GRO/KC |
Number of Cells | 26 | 22 | 25 | 18 |
Diameter, μm | 20.0 ± 0.8 | 21.2 ± 0.7 | 22.8 ± 0.5 | 20.2 ± 0.9* |
Cell Capacitance, pF | 17.6 ± 1.3 | 20.0 ± 1.2 | 19.0 ± 1.3 | 16.8 ± 1.7* |
Resting Potential, mV | -63.0 ± 1.6 | -56.0 ± 1.4** | -64.6 ± 1.4 | -55.4 ± 1.9 ** |
Input Resistance, MΩ | 1244.0 ± 144.3 | 986.1 ± 99.4 | 1062.0 ± 64.6 | 1427.4 ± 92.3** |
AP Rheobase, pA | 60.4 ± 8.4 | 21.1 ± 2.1** | 76.2 ± 14.2 | 51.1 ± 11.2* |
AP Threshold, mV | -19.7 ± 0.9 | -28.6 ± 1.4** | -16.6 ± 0.6 | -25.4 ± 1.3** |
AP Rising Rate, mV/ms | 106.8 ± 9.6 | 112.5 ± 10.7 | 103.4 ± 8.8 | 102.4 ± 12.0 |
AP Falling Rate, mV/ms | 49.7 ± 4.8 | 61.9 ± 7.3 | 43.4 ± 3.8 | 39.9 ± 5.0** |
AP Amplitude, mV | 64.8 ± 1.7 | 74.8 ± 1.8** | 63.1 ± 1.9 | 71.1 ± 1.5 ** |
AP Duration, ms | 6.6 ± 0.4 | 7.3 ± 0.5 | 8.3 ± 0.5 | 14.0 ± 1.0** |
AHP Amplitude, mV | 3.5 ± 0.5 | 5.9 ± 0.6 ** | 3.0 ± 0.8 | 4.5 ± 0.7 |
AHP Duration, ms | 10.8 ± 2.4 | 14.7 ± 0.8* | 7.7 ± 1.7 | 9.9 ± 1.4 |