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Figure 5 | Molecular Pain

Figure 5

From: Effect of excitatory and inhibitory agents and a glial inhibitor on optically-recorded primary-afferent excitation

Figure 5

The effect of glutamate receptor antagonists and a glial metabolism inhibitor on presynaptic excitation. A, Spatially averaged time course of presynaptic excitation in the substantia gelatinosa in spinal dorsal horn elicited by high-intensity stimulation to the dorsal root in a control slice (thin line), and that after the application of CNQX (bold line). B, Spatially averaged time courses of presynaptic excitation before (thin) and after (thick) the application of D-AP5 and CNQX. C, Spatially averaged time courses of presynaptic excitation before (thin line) and after (bold line) the application of D-AP5 and CNQX and MFA. D, The bar graph summarizes the increases in presynaptic excitation induced by the application of CNQX, by D-AP5 and CNQX, and by D-AP5, CNQX, and MFA.

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Molecular Pain

ISSN: 1744-8069

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