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Figure 4 | Molecular Pain

Figure 4

From: Differential regulation of morphine antinociceptive effects by endogenous enkephalinergic system in the forebrain of mice

Figure 4

Effect of morphine on the sink current evoked in the S1 by laser pulses (10 W and 20 ms duration). (A) Example of laser evoked CSD profiles in the S1 before and after morphine treatment (10 mg/kg) in WT (upper panel) and KO (lower panel) mice. (B) Statistical analysis of the effect of morphine on sink 1a, sink 2a and sink 2b in WT and KO mice. Reversibility of the effect was evaluated by treatment with naloxone (0.7 mg/kg). * p < 0.05. ** p < 0.01.

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