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Table 3 Pain parameters and clinical data for CBP and OA patients

From: A preliminary fMRI study of analgesic treatment in chronic back pain and knee osteoarthritis

CBP

OA

 

Session1

Session2

p-value

 

Session 1

Session 2

p-value

Pain Int.

49.5 ± 19

27.2 ± 18.1

0.034

Pain Int.

39.6 ± 14.3

37.2 ± 12.6

0.513

VAS

62.3 ± 9.9

34.3 ± 19.6

0.008

VAS

55.5 ± 12.3

52.5 ± 11.9

0.501

Affective

3.4 ± 4.5

2.3 ± 4.4

0.331

Affective

0.5 ± 1.0

1.5 ± 1.0

0.308

Sensory

11.1 ± 9.2

8.3 ± 10.1

0.482

Sensory

9.3 ± 1.7

6.3 ± 3.9

0.334

NPS (N)

17.8 ± 13.7

9.9 ± 8.4

0.055

Pain (W)

10.0 ± 1.6

9 ± 2.4

0.252

Unpleas. (N)

5.2 ± 1.3

3.4 ± 2.1

0.094

Stiffness (W)

5.0 ± 1.4

5.0 ± 1.4

1.000

Deep (N)

6.6 ± 1.7

3.5 ± 2.6

0.082

Activity (W)

35.2 ± 4.9

31.5 ± 9.1

0.243

Surface (N)

4.2 ± 1.9

1.9 ± 2.3

0.025

Pain Int./Pr

29.3 ± 10.4

23.1 ± 8.3

0.0622

  1. Session 1 = prior to use of Lidoderm therapy; Session 2 = after 2 weeks of Lidoderm therapy. Pain Int. = mean pain rating during the scan; Pain Int./Pr = mean pain rating during the scan divided by normalized applied pressure.VAS = visual analog scale; Unpleas = unpleasantness; VAS, Affective and Sensory are from McGill short form. N = Neuropathic Pain Scale; W = WOMAC. All parameters are expressed as μ ± S.D. p values were computed using a paired t-test.