Figure 2
From: Cutaneous tactile allodynia associated with microvascular dysfunction in muscle
Bilateral laser Doppler traces during ischemia and reperfusion. Simultaneous ipsilateral and contralateral representative blood flow measures (arbitrary flux units) in a rat with an O-ring tourniquet placed on the ipsilateral ankle for 3 h between 10 and 190 min. The tourniquet resulted in a complete block of blood flow in the ipsilateral hind paw during the ischemic period, while no change in blood flow was observed in the contralateral hind paw. Reperfusion occurred at 190 min, when the tourniquet was removed, causing an intense and prolonged hyperemia in the ipsilateral hind paw, with only a minor transient change in blood flow in the contralateral hind paw.