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Figure 6 | Molecular Pain

Figure 6

From: Expression of AMPA receptor subunits at synapses in laminae I–III of the rodent spinal dorsal horn

Figure 6

Immunostaining for GluR1, GluR2 and GluR3 in AMPAr knock-out and wild-type mice. Confocal images showing parts of the superficial dorsal horn from a wild-type (w.t.) mouse and from mice in which the genes coding for GluR1, GluR2 and GluR3 (gria1, 2 and 3) had been knocked out. Each row shows staining in a different mouse, and in each case staining for GluR1 (red) is shown in the left column, followed by staining for GluR2 (blue) and GluR3 (green), with a merged image in the right column. Note the lack of staining for the corresponding subunit in each of the knock-out mice. Images show projections of 8 optical sections at 0.3 μm z-separation. Scale bar = 5 μm.

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