Figure 1
From: Single dose of morphine produced a prolonged effect on dopamine neuron activities
Morphine alters the firing rate and pattern of the VTA DA neurons in naïve rats. The firing activities were recorded before and after morphine injection (5 mg/kg, i.v.). A: firing rate of a representative DA neuron. B: distribution of firing rate in the same neuron. C: representative segment of firing spike train recorded from a DA neuron before and after morphine treatment. D: spectral chart before (upper panel) and after (lower panel) morphine treatment. SO: slow oscillation.