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Figure 6 | Molecular Pain

Figure 6

From: Mechanisms involved in an increment of multimodal excitability of medullary and upper cervical dorsal horn neurons following cutaneous capsaicin treatment

Figure 6

pERK-LI cells in Vc after graded cold stimulus of the lateral facial skin in rats with capsaicin or vehicle application to the skin. A-F: Photomicrographs of Vc following 5, 15 and 25°C stimuli of the skin in vehicle- (A-C) or capsaicin-treated (D-F) rats. G-L: Rostro-caudal distribution of pERK-LI cells in Vc and C1-C2 following graded cold stimulus of the skin in vehicle- (G-I) and capsaicin-treated rats (J-L). M: Mean number of pERK-LI cells in Vc and C1-C2 following graded cold stimulus of the skin in vehicle- (open columns) and capsaicin-treated (solid columns) rats. *: p<0.05, **: p<0.01, $: p<0.05 (Veh + cold vs. Cap + cold), $$: p<0.01 (Veh + cold vs. Cap + cold), #: p<0.05 (Cap + cold vs. Cap), ##: p<0.01 (Cap + cold vs. Cap). Veh: vehicle for capsaicin, Cap: capsaicin.

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