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Figure 8 | Molecular Pain

Figure 8

From: Mechanisms involved in an increment of multimodal excitability of medullary and upper cervical dorsal horn neurons following cutaneous capsaicin treatment

Figure 8

Effect of subcutaneous capsazepine injection into the facial skin on the noxious heat, cold or mechanical stimulus-induced pERK-LI cells in capsaicin-treated rats. A and B: Vehicle or capsazepine injection following 50°C stimulation of lateral facial skin in capsaicin-treated rats. C and D: Vehicle or capsazepine injection following 5°C stimulation of the skin in capsaicin-treated rats. E and F: Vehicle or capsazepine injection following 60g stimulation of the skin in capsaicin-treated rats. G: Mean number of pERK-LI cells in Vc and C1-C2 following noxious heat, cold or mechanical stimuli of the skin in capsaicin-treated rats receiving capsazepine (solid columns) or vehicle (open columns) subcutaneously injection. **: p<0.01. Veh for Capz: vehicle for capsazepine, Capz: capsazepine, Cap: capsaicin.

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