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Figure 4 | Molecular Pain

Figure 4

From: Long-term actions of interleukin-1β on delay and tonic firing neurons in rat superficial dorsal horn and their relevance to central sensitization

Figure 4

A – D. Bar graphs illustrating effect of IL-1β on amplitude and interevent interval of sIPSC's and sEPSC's in tonic and delay cells. Error bars = S.E.M., graphs produced from same data as used for cumulative probability plots. E – L. Reanalysis of the data in A-D shown as cumulative probability plots. For EPSC's in tonic cells (E and F), 800 events from 8 neurons analyzed in control (minimum # of events analyzed per cell = 100), 563 events from 6 neurons analyzed in IL-1β (minimum # of events analysed per cell = 63); For IPSC's in tonic cells (G and H), 600 events from 6 neurons analyzed in control (minimum # of events analyzed per cell = 100), 239 events analyzed in 5 neurons in IL-1β (minimum # of events analysed per cell = 37); For EPSC's in delay cells (I and J), 699 events analyzed in 7 control neurons (minimum # of events analysed per cell = 99), 500 events analyzed in five neurons in IL-1β (minimum # of events analyzed per cell = 100); For IPSC's in delay cells (K and L), 751 events analyzed in 4 control neurons (minimum # of events analysed per cell = 151), 1085 events analyzed in 6 neurons in IL-1β (minimum # of events analysed per cell = 85). M and N. Sample recordings of sEPSCs at -70 mV and sIPSC's at 0 mV.

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Molecular Pain

ISSN: 1744-8069

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