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Table 6 Patient demographics.

From: Genetic variation in the Catechol-O-Methyltransferase (COMT) gene and morphine requirements in cancer patients with pain

 

Haplotype 1

P value

 

Carriers

Non-carriers

 

Age

63 (13)

64 (12)

0.68

Gender:

   

   Male

68 (60%)

44 (53%)

0.38

   Female

46 (40%)

39 (47%)

 

Tumour diagnosis:

   

   Urological

38

19

0.80

   Lung

20

17

 

   Breast

25

19

 

   Gastrointestinal

7

10

 

   Haematological

10

6

 

   Others

14

12

 

Karnofsky performance status

67 (14)

66 (13)

0.36

Creatinine serum (μmol/l)

86 (28)

87 (39)

0.48

Albumin serum (g/l)

33 (5)

32 (5)

0.12

Time since diagnosis (months)

45 (52)

31 (43)

0.03a

Time since morphine treatment started (months)

3.4 (7.8)

3.6 (5.9)

0.47

Survival time after study (months)

5.7 (6.2)

4.8 (5.5)

0.23

  1. Numbers in the table are given as mean (SD) or absolute numbers (%)
  2. a Mann-Whitney U test for 2 independent samples
  3. Patient demographics for carriers and non-carriers of haplotype 1.