Skip to main content
Figure 4 | Molecular Pain

Figure 4

From: Gene transfer of GLT-1, a glial glutamate transporter, into the spinal cord by recombinant adenovirus attenuates inflammatory and neuropathic pain in rats

Figure 4

Effect of spinal GLT-1 gene transfer on the induction of allodynia in the pSNL-induced neuropathic pain model. PBS (open circle), Ad-EGFP (open square), or Ad-GLT-1 (closed square) was infused intraspinally (arrows in the graph). Seven days later (day 0), pSNL was performed (arrows) and 50% withdrawal thresholds of the ipsilateral (A) and contralateral (B) paws were measured with the von Frey filament test on the indicated days. Data are presented as the mean ± S.E.M. *P < 0.05, ***P < 0.001 vs PBS; #P < 0.05, ###P < 0.001 vs Ad-EGFP, n = 6–9.

Back to article page