Figure 1

Increased mechanical and thermal sensitivity after SNE induction. A: hindpaw withdrawal thresholds (mean ± S.E.M.) to mechanical stimuli on the ipsilateral side (n = 6 rats) are significantly decreased compared to contralateral side and naïve rats (n = 6) at 2 days after SNE surgery. Note that the decreases persist to the last day of measurements. B: hindpaw withdrawal latency (mean ± S.E.M.) from thermal stimuli on the ipsilateral side is also significantly reduced by the 3^rd day after SNE. *, significant difference from other group means.