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Figure 3 | Molecular Pain

Figure 3

From: Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model

Figure 3

met-Enkephalin immunohistochemical staining in spinal cord (T9–10). A. The spinal cord from a naïve rat is shown for comparison to (B) the spinal cord of animals with diet-induced pancreatitis at week 10. C. The expression of met-ENK after application of vehicle or HSV-β-gal is similar to naïve rats (A). D. Met-ENK expression was significantly increased in HSV-ENK vector-treated animals compared to controls. Met-ENK in the dorsal horn (laminae I–II) of the thoracic spinal cord was increased bilaterally.

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